Standard Operating Procedure (SOP) Templates

Cal/OSHA requires the establishment of standard operating procedures for work with hazardous chemicals

Guidance Reference Document

Campus Standard Operating Procedures: Requirements & Recommendations


This requirement is stated in 8 CCR §5191 (Occupational Exposure to Hazardous Chemicals in Laboratories, “Laboratory Standard”) under the provisions of the Chemical Hygiene Plan. SOPs document the laboratory-specific procedures for the safe handling, storage, and disposal of hazardous chemicals. Principal investigators and laboratory supervisors are responsible for establishing SOPs relevant to health and safety for laboratory activities involving hazardous chemicals.

Chemicals classified as “Particularly Hazardous Substances” have additional SOP requirements. Particularly Hazardous Substances include acutely toxic chemicals, reproductive toxins, and “select carcinogens.” For these materials, specific consideration shall be given to the following elements, which shall be included where appropriate:

  1. The establishment of a designated area.
  2. The use of containment devices, such as fume hoods or glove boxes.
  3. Procedures for safe removal of contaminated waste.
  4. Decontamination procedures.

The SOP templates have been prepared under direction of the UC Davis Chemical and Laboratory Safety Committee (CLSC). These templates include a general SOP template and several control-banded SOP templates. The CLSC has also approved campus minimum SOP requirements that leverage the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Hazard codes to aid in inventory searches, but depending on the manufacturer, these may not always be included on the Safety Data Sheet (SDS). If the SDS only has the hazard statement, this can be be translated to the corresponding Hazard code and then compared to the guidance reference document. Please contact or your Laboratory Safety Professional with any questions or for assistance in implementing the requirements. Additional shop-specific SOP resources can be found in the UC Davis Shop Safety Manual.

For assistance in developing laboratory-specific SOPs or determining whether a chemical is suitable for inclusion in a control band, contact  Do NOT use the Listed Carcinogen SOP without consulting EH&S.