Definitions

• Biohazardous Material
• Biological materials that present a risk or potential risk to the health of humans, animals, or the environment.
• Biological Use Authorization (BUA)
• Document that outlines research involving recombinant DNA technology (including viral vectors), and/or materials that are infectious (or potentially infectious) to plants, animals, or humans. The BUA must be approved by the UC Davis Institutional Biosafety Committee (IBC) prior to EH&S signing off on the Animal Care and Use Protocol.
• Environmental Hazard
• Environmental hazards are indicated by Globally Harmonized System (GHS) hazard codes H400 (Very toxic to aquatic life) and H410 (Very toxic to aquatic life with long lasting effects). Many materials that are environmental hazards are also health hazards; however, there are instances where a material does not pose a health hazard to animal care staff but may still be an environmental hazard. Materials that are only classified as environmental hazards require a Vivarium Hazard Safety Sheet (VHSS) to ensure proper disposal. They must be listed in Sections 14a and 14b of the Animal Care and Use Protocol and in Section 8 to alert animal care staff to reference the VHSS for proper disposal procedures. 
• Hazard Communication Program
• All animal care spaces at UC Davis fall under the Hazard Communication Program. This program is designed to increase employee awareness of any chemicals and/or medications used in the workplace by providing information about these materials, identifying the associated hazards and potential harmful effects, and how to protect from the risks of those hazards. The Hazard Communication Program must clarify standard PPE practices and animal handling requirements to protect workers from Standard of Care medications, procedures to protect workers from exposure to hazardous materials, as well as the facility-determined method for PIs/researchers to alert vivarium staff that a hazardous material or Standard of Care medication is present (e.g., hazard cards, door signs). Refer to EH&S webpage regarding the Hazard Communication Program in Animal Care Spaces (coming soon) for more details.
• Hazardous Chemical
• Hazardous chemicals cover a broad range of chemicals as described in 8 CCR §5194. A hazardous chemical is any chemical which is classified as a physical hazard, or a health hazard, an asphyxiant, combustible dust, pyrophoric gas, a hazard not otherwise classified, or is included in the List of Hazardous Substances (8 CCR §339). As it pertains to this policy, hazardous chemicals are carcinogens (GHS hazard codes H350, H351), reproductive hazards (GHS hazard codes H340, H341, H360, H361), antineoplastics, chemicals with unknown hazards, Schedule I Controlled Substances/hallucinogenic material, or any material whose hazards cannot be sufficiently addressed via the hazard communication program. These chemicals will receive a VHSS detailing the proper handling and disposal requirements of that material.
• Hazardous Material
• Hazardous materials in this policy covers all categories of hazardous chemicals, recombinant/biohazardous material, and radioactive material. All hazardous materials must be listed Sections 14a and 14b of, the Animal Care and Use Protocol (ACUP). Hazardous materials that have hazards that cannot be sufficiently addressed via the hazard communication program will receive a VHSS detailing the proper handling and disposal requirements of that material and be included in Section 8 of the Animal Care and Use Protocol.
• Injury and Illness Prevention Program (IIPP)
• The purpose of an Injury & Illness Prevention Program is to establish a management framework for reducing the risks associated with workplace injuries and illnesses, and identifying what is required to promote the safety and health, and create an outline of policies and procedures to achieve safety and health goals. All areas on campus, including but not limited to, research areas and animal care spaces, are required by Cal/OSHA to have an IIPP.
• Radiation Use Authorization (RUA)
• Work with ionizing radiation requires a Radiation Use Authorization from the Radiation Safety Committee (if necessary), the Radiation Safety Officer, Alternate Radiation Safety Officer, or designee to conduct specific research using radionuclides. Research involving ionizing radiation in animal research requires an RUA prior to EH&S signing off on the Animal Care and Use Protocol.
• Radioactive Material
• Any material, solid, liquid, or gas that emits ionizing radiation spontaneously.
• Recombinant Material
• Nucleic acids, proteins, cells, or organisms that are made by combining genetic material from two different sources.
• Standard of Care
• Standard of care medications are those that are FDA approved for use in humans and/or animals, AND that do NOT appear on the NIOSH “List of Hazardous Drugs in Healthcare Settings”. These medications do not require a VHSS whether being used clinically or as part of an approved IACUC protocol. This condition holds true only if the medications are administered in a veterinary formulary approved route and appropriate dose for the application: any medications administered outside of an approved route will be subject to review and may require a VHSS.
• Viral Vectors
• A modified form of a virus used to deliver genetic material or "payload" into a cell.  Viral vectors can have specific hosts and the gene products encoded by the genetic material can influence safe handling and disposal practices, so be sure to refer to the relevant VHSS for safety information.
• Vivarium Hazard Safety Sheet (VHSS)
• The VHSS is a tool to inform animal care staff of a specific hazard that exists in the vivarium and to inform of proper administrative and engineering controls, PPE, and waste disposal requirements. A VHSS is created for protocols where animals will be administered hazardous chemicals, recombinant/biohazardous material, and radioactive material, as well as for environmental hazards or materials with non-routine disposal requirements to ensure proper handling.