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Biological Use Authorization (BUA)

Research that involves any of the following activities or materials requires a Biological Use Authorization (BUA).

  1. Research involving recombinant DNA technology, except projects that are exempt under the NIH Guidelines for Research Involving Recombinant DNA Molecules.  For exempt rDNA activities, please see our FAQ entry on this topic.
  2. Work with materials that are infectious (or potentially infectious) to plants, animals, or humans (including replication-defective viral vectors).
  3. Working with any material that falls under the Cal OSHA Bloodborne Pathogen Standard.  This includes any work with human cell lines, human blood or blood products, and human body fluids.  At UC Davis, work with non-human primate (NHP) cells, established NHP cell lines, and NHP blood or blood products also requires a BUA.
  4. Storage of biohazardous materials that are not being used.


No work with biological agents or recombinant DNA is permitted on the UC Davis campus before approval is granted by the Institutional Biosafety Committee (IBC).  BUA approvals can take approximately eight weeks to process once a submission has been received.

BUA Submission Deadline Biosafety Committee Meeting Schedule
February 2, 2015 February 23, 2015
February 27, 2015 March 16, 2015
April 1, 2015
April 20, 2015
May 1, 2015

May 18, 2015



New Online Form: Biosafety Information Online (BIO)


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