Sheep and Goat Anesthetic and Analgesic drug dosages

	DOSE	ROUTE	FREQUENCY	REFERENCE	NOTES

PREMEDICATION
Acepromazine	0.05-0.2 mg/kg	SC, IM, IV		36	as an adjunct to anesthesia
Diazepam	0.25 mg/kg	IV			as an adjunct to anesthesia
	0.55-1.1 mg/kg	IM

ANESTHETICS
Ketamine	10 mg/kg	IV		36	best given with a sedative
Telazol	3 mg/kg	IM
Propofol	5 mg/kg	IV
Isoflurane, Halothane	to effect	inhalation

OPIOIDS
Morphine	up to 10 mg total dose	IM		1a
	< 10 mg total	IM	q. 4 hrs	16
Meperidine	up to 200 mg total dose	IM		1a
	< 200 mg total	IM	q. 4 hrs	16
Buprenorphine	0.005 mg/kg	IM	q. 12 hrs	1a	Goats
	0.005 - 0.01 mg/kg	IM	q. 4-6 hrs	16	Sheep
	0.006 mg/kg	IV	q. 4 hrs	22	analgesia onset up to 45 min., lasted 3.5 hrs, excitement seen with IV route of administration
Nalbuphine	1 mg/kg	SC		9	onset 15-30 min., analgesia lasted 120 min. (sheep)
Butorphanol	0.5 mg/kg	SC		9	lasted 120 min. (sheep)
	0.05-0.2 mg/kg	IV			analgesia lasted 1-2 hrs, depending on dose, excitement at higher doses, do not exceed 0.2 mg/kg IV (23)

NON-OPIOIDS
Xylazine	0.05-0.2 mg/kg	IM		1a
Medetomidine	0.025 mg/kg	IM

LOCAL ANESTHETICS
Lidocaine	0.5-1.0 %			27	maximum safe total dose 6 mg/kg
Mepivacaine	0.5-1.0%			27	maximum safe total dose 6 mg/kg
Bupivacaine				27	maximum safe total dose 2 mg/kg

ANESTHETIC ANTAGONIST
Naloxone	0.015-0.04 mg/kg	SC, IP, IV			reverses opioids
Nalbuphine	1 mg/kg	IV, IM			partial reversal of opioids
Yohimbine	0.1-0.15 mg/kg	IV			reverses xylazine
Atipamezole	0.1-0.2 mg/kg	IV			reverses medetomidine

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