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Dog Anesthetic and Analgesic drug dosages

 

  DOSE ROUTE FREQUENCY REFERENCE NOTES
           
PREMEDICATION          
Atropine 0.022-0.044 mg/kg SC, IM
Glycopyrolate 0.011 mg/kg IM, SC
Acepromazine 0.03-0.1 mg/kg SC, IM as an adjunct to anesthesia
Diazepam 0.05 mg/kg IM, IV as an adjunct to anesthesia
           
ANESTHETICS          
Ketamine/Diazepam 10/0.5 mg/kg IV induction and chemical restraint
Telazol 5-10 mg/kg IM 36
Propofol 4-8 mg/kg IV 36
Thiopental 9-18 mg/kg IV
Isoflurane, Halothane to effect inhalation
           
OPIOIDS          
Morphine 0.1-0.4 mg/kg IM q. 4-6 hrs 1a, 1b
0.25-1.25 mg/kg SC, IM, IV q. 4-6 hrs
2.5 mg/kg SC, IM q. 4-6 hrs 2 profound sedation and analgesia
Codeine 2.2 mg/kg SC 1a supresses cough
0.25-0.8 mg/kg PO q. 6 hrs 15 with paracetamol - acetaminophen
Fentanyl patch Transdermal
Meperidine 2-10 mg/kg IM, SC q. 2-3 hrs 30 short duration of 60-90 min
Methadone 0.25-1.0 mg/kg SC 1b
Pentazocine 2 mg/kg IM q. 4 hrs 15, 16 short duration of 45 min (Ref 30)
Buprenorphine 0.01-0.02 mg/kg  SC, IM, IV q. 12 hrs 1a, 4, 16 better if given during anesthesia, 0.01 lasts < 4 hrs
Nalbuphine 0.5-2.0 mg/kg SC, IM, IV q. 3-8 hrs 16
Butorphanol 0.2-0.4 mg/kg SC, IM, IV q. 2-5 hrs 16
0.2-0.8 mg/kg SC q. 1 hr 21 effective visceral analgesia lasted 23-53 min
30 better if given during anesthesia
Oxymorphone 0.025-0.22 mg/kg SC, IM, IV q. 6 hrs 1a, 1b
           
NON-OPIOIDS          
Medetomidine 0.05 mg/kg IM
Phenylbutazone 15 mg/kg PO, IV q. 8 hrs 1b, 10
Carprofen 2 mg/kg PO q. 12 hrs
Aspirin 10 mg/kg PO q. 6-12 hrs 1a, 1b, 8, 15
Flunixin 0.5-2.2 mg/kg PO, IM, IV q. 24 hrs 1a, 1b for no longer than three days
Ibuprofen 5-10 mg/kg PO q. 24-48 hrs 1a, 1b
5 mg/kg/day PO q. 24 hrs divided BID
Meloxicam 2 mg/kg PO q. 12 hrs
Meclofenamic acid 2.2 mg/kg PO q. 24 hrs 1b
1.1 mg/kg PO q. 24 hrs for 5-7 days
Naproxen 5 mg/kg initially
1.2-2.8 mg/kg PO q. 24 hrs 1a, 8
Acitaminophen 10-20 mg/kg plus codeine q. 6 hrs 15
           
ANESTHETIC ANTAGONIST          
Naloxone 0.015-0.04 mg/kg SC,IM,IV reverses opioids
Nalbuphine 0.75-3 mg/kg SC partial reversal of opioids
Yohimbine 0.1-0.15 mg/kg IV reverses xylazine
Atipamezole 50-400 ug/kg IV reverses medetomidine; 5 times the dose of Medetomidine IV or IM