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SafetyNet #4 - Partial List of Incompatible Chemicals

 

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The following list is to be used only as a guide. Specific incompatibilities are listed in the Material Safety Data Sheets. Consult Betherick’s Handbook of Reactive Chemical Hazards (Urben, P.G.; 6th Ed.; Butterworth-Heinemann: London, 200; book and CD-ROM) for an extensive listing and thorough discussion of chemical incompatibilities.

 

Example of Incompatible Chemicals*

 

Chemical:

Incompatible With:

Acetic acid

Oxidizing agents, e.g., chromic acid, nitric acid, hydroxyl compounds, ethylene glycol, perchloric acid, peroxides, permanganates

Acetone

Nitric acid and sulfuric acid, other oxidizing agents

Acetylene

Chlorine, bromine, copper, fluorine, silver, mercury

Alkali and alkaline earth metals (such as powdered aluminum or magnesium, calcium, lithium, sodium, potassium)

Water, carbon tetrachloride, other chlorinated hydrocarbon compounds, carbon dioxide, halogens

Ammonia (anhydrous)

Mercury (e.g., in manometers), chlorine, calcium hypochlorite, iodine, bromine, hydrofluoric acid

Ammonium nitrate

Acids, powdered metals, flammable liquids, chlorates, nitrites, sulfur, finely divided organic or combustible materials

Aniline

Nitric acid, hydrogen peroxide

Arsenical materials

Reducing agents

Azides

Acids

Bromine

See chlorine

Calcium oxide

Water

Carbon (activated)

Calcium hypochlorite, other oxidizing agents

Chlorates

Ammonium salts, acids, powdered metals, sulfur, finely divided organic or combustible materials

Chlorine

Ammonia, acetylene, butadiene, butane, methane, propane (or other petroleum gases), hydrogen, sodium carbide, benzene, finely divided metals, turpentine

Chlorine dioxide

Ammonia, methane, phosphine, hydrogen sulfide

Chromium trioxide (chromic acid)

Acetic acid, naphthalene, camphor, glycerol, alcohol, flammable liquids

Copper

Acetylene, hydrogen peroxide

Cyanides

Acids

Flammable liquids

Ammonium nitrate, chromic acid, hydrogen peroxide, nitric acid, sodium peroxide, halogens

Hydrocarbons (e.g., butane, propane, benzene)

Fluorine, chlorine, bromine, chromic acid, sodium peroxide, other oxidizing agents

Hydrocyanic acid (anhydrous)

Alkali

Hydrofluoric acid

Potassium permanganate, sulfuric acid

Hydrogen sulfide

Metal oxides, powdered copper, oxidizing gases

Hypochlorites

Acids, activated carbon, ammonia

Iodine

Acetylene, ammonia (aqueous or anhydrous), hydrogen

Mercury

Acetylene, fulminic acid, ammonia

Nitrates

Powdered metals and non-metals, metal sulfides, flammable/combustible liquids

Nitric acid

Acetic acid, aniline, chromic acid, hydrocyanic acid, hydrogen sulfide, flammable liquids and gases, copper, brass, heavy metals, alkalis

Nitrites

Ammonium salts, amides, phosphides, reducing agents

Nitroparaffins

Acids, bases, amines, halides

Oxalic acid

Silver, chlorites, urea

Oxygen

Oils, grease, hydrogen, and other reducing agents, including flammable liquids, solids or gases

Perchlorates

See Chlorates

Perchloric acid

Reducing agents such as acetic anhydride, bismuth and its alloys, alcohols, paper, wood, grease, oils

Phosphorous (white)

Air, oxygen, alkalis, halogens, halogen oxides, oxidizing agents

Potassium

Carbon tetrachloride, carbon dioxide, water

Potassium permanganate

Glycerol, ethylene glycol, benzaldehyde, other reducing agents, sulfuric acid

Sodium

Carbon tetrachloride, carbon dioxide, water

Sodium peroxide

Ethyl and methyl alcohol, glacial acetic acid, acetic anhydride, benzaldehyde, carbon disulfide, glycerin, ethylene glycol, ethyl acetate, methyl acetate, furfural

Sulfides

Acids

Sulfuric acid

Permanganates, water, aqueous solutions, reducing agents, chlorates, perchlorates, nitric acid


*Reference: Safety in Academic Chemistry Laboratories Volume 1. Published by the American Chemical Society, Committee on Chemical Safety: 7th Edition, Appendix IV. Reprinted by permission..

For additional information, contact your EH&S Safety Advisor, EH&S at 530-752-1493 or ehsdesk@ucdavis.edu.

Reviewed/Revised. 05/2007
DMD